The clinic that Lucy visits is called the "Callahan Institute" and Dr. Keats (Dan Aykroyd) states that it is "funded out of Sandusky, Ohio by T.B. Callahan, the automotive components tycoon". In Tommy Boy (1995), Aykroyd plays a rival automotive components tycoon that is attempting to purchase Tom (T.B.) Callahan's company.
Henry makes a video for Lucy to remind her of the events that have occurred since her accident. One of the items is "Red Sox win the World Series..." followed by "... Just Kidding". During the year of the film's release, the Red Sox actually broke an 86-year drought and won the World Series. Drew Barrymore made the movie Fever Pitch (2005) about an avid Red Sox fan and they filmed the final scene on the Busch Stadium field while the Red Sox celebrated winning the 2004 World Series.
The wedding portrays Henry as being Jewish, however during the movie it is said that he consumes SPAM, which is mostly pork products and therefore not kosher. However, not all Jews observe the religious laws.
In the first shot of Henry, Lucy, Doug and Marlin driving to the Callahan Institute, Henry and Lucy are sitting in the back seat and Lucy's hair is blowing around because the window is down. In all other shots of them driving, Lucy's hair isn't blowing around anymore and no one is ever shown rolling up the window.