Anegan

Kiran

Madhu / Samudhra / Kalyani

Mallika / Meera

Commissioner Gopinath

Samudhra's Father / Radhakrishnan

Moorthy

Mallika's Husband / Jagan

Madhu's Mother

Ashwin's Father

Dr. Radhika

Guruji

Genie

KV Anand revealed that Ilayathalapathy Vijay was his first choice for Anegan as he wrote the script with the actor in his mind. But unfortunately, due to his prior commitments for AR Murugadoss' Kaththi, Vijay had turned down the film. The cinematographer-turned director even mentioned that it was Vijay who had put forward Dhanush's name for the film. So that's how Dhanush landed himself into Anegan.

The shooting started on 2nd September in Puducherry.

In preparation for the role of Amyra Dastur. she was asked to see Tamil films. She also took Tamil lessons from Dhanush to get her dialogues right.