The picture of Doctor Weird's castle in New Jersey is actually taken from an episode of The Real Adventures of Jonny Quest (1996) called "Escape to Questworld". It's a shot of The Belle Isle Institute, where Dr. Jeremiah Surd is housed. The shot was originally the Himalayan outpost from the "Monster in the Monastery" episode of the 1964 series.
Emory and Oglethorpe, the Plutonians, share their names with two universities in Atlanta, GA. Williams Street - the company that produces the show - is based in Atlanta.
Schooly-D wrote the theme song on the same day it was recorded, while riding in a limo on his way to the studio to record the theme song. Dave Willis and Matt Maiellaro provided the backup vocals.
Master Shake: [Frylock is about to revive Carl, whose body has been recreated from a mass of eyeballs]
What a minute. Before you turn him on - do you think he'll be able to be able to see us?