Michael Parks, who plays Ambrose Bearse, also appeared in the original From Dusk Till Dawn (1996), playing a completely different character. His real life son, James Parks, had a small role in From Dusk Till Dawn 2: Texas Blood Money (1999).
Shortly after Danny Trejo's resident bartender character changes into a vampire, he's soon replaced by another taller, and obviously skinner actor in vampire makeup, wearing the same clothes, and Danny is never seen again.
The subtitle of the film, "The Hangman's Daughter," is taken from the title of a short story co-authored by Ambrose Bierce (who appears as a character in the film) - "The Monk and the Hangman's Daughter," Ambrose Bierce and Adolphe Danziger De Castro, 1911.