Jon Heder's big dance scene was the last scene scheduled and film ran out while shooting it. The sequence was edited together from less than 10 minutes of his dancing.
Having the food plates spell out names in the opening credits was Aaron Ruell's idea. The rest of the sequence was designed and executed by Pablo Ferro.
When Grandma is telling Napoleon and Kip she is going to be gone for a couple of days, the bag of chips behind Napoleon on the kitchen counter change positions.
When Napoleon is watching Lyle shoot the cow and the bus drives in between them, the camera, tripod, and several members of the crew can be seen reflected in the glass on the bus door.