Nurse Jackie

Nurse Jackie

Jackie Peyton

Zoey Barkow

Eddie Walzer

Thor Lundgren

Kevin Peyton

Grace Peyton

Gloria Akalitus

Dr. Fitch Cooper

Fiona Peyton

Dr. Eleanor O'Hara

Sam

Nurse Jackie is the fifth television series to feature both Edie Falco and Paul Schulze; the other four being Homicide: Life on the Street (1993), Oz (1997), the The Sopranos (1999), and New York Undercover (1994). New York Undercover is the only one of the five that the two were not featured in the same episode.

The East 25th Street entrance of the William and Anita Newman Vertical Campus of Baruch College in the Gramercy section of Manhattan served as the entrance façade of All Saints Hospital at which Nurse Jackie and her colleagues work during the first three seasons. In the fourth season, the hospital's entrance façade was changed to Bellevue Hospital at East 27th Street and First Avenue.

Edie Falco and Paul Schulze appeared in the indie crime drama Laws of Gravity before the fame.