David Duchovny's appearances on the show focused on his attraction to Larry. This is a joke that has outlived the Sanders show itself, resurfacing, among other places, on Duchovny's show The X-Files (1993) (in the episode "Hollywood A.D.", Garry Shandling, appears as himself, Gillian Anderson's character comments to Duchovny's character "I think that Téa Leoni has a little crush on you...I think that Shandling likes you a bit too.") and in a skit filmed for The 56th Annual Primetime Emmy Awards (2004).