During the flashback of Gleick's interview of Krane, he says that Krane's blood alcohol level was "2.5". He most likely meant .25, or just over three times the limit deemed legally impaired (in most places). For Krane to have been at 2.5, he would have been five times over what is most likely a fatal amount.
The first time injecting the memory serum on himself, Dr. Krane inserts the needle in his arm in the wrong direction; against the flow of blood in his body. Any medical professional knows venous injections are only given in the same direction as blood return to the heart.