Her parents, Lina and Domenico Sigismondi, were opera singers.
Studied painting and illustration at the Ontario College of Art and Design.
Daughter, Tosca Vera Sigismondi-Berlin, was born in October 2004. She was named after the Italian opera "Tosca".
Directed music videos for Marilyn Manson, David Bowie, Tricky, Filter, The Jon Spencer Blues Explosion, Interpol, Living Things, Christina Aguilera, Sigur Ros, Incubus, The Cure, The White Stripes, Muse, Billy Talent and more.
Husband is Lillian Berlin, lead singer of the rock band Living Things.