Was the runner-up for the 2004 Los Angeles Film Critics Association Award for Best Supporting Actress for her performance in 21 Grams (2003).
Has worked with Kristen Stewart twice. Once in The Cake Eaters (2007) and again in Welcome to the Rileys (2010).
Was the 137th actress to receive an Academy Award; she won the Best Supporting Actress Oscar for The Fighter (2010) at The 83rd Annual Academy Awards (2011) on February 27, 2011.
She is a natural redhead.
Mother is Peggy Chessington Leo, a Californian teacher, and father, Arnold Leo, is an editor at Grove Press, and a fisherman spokesman for the East Hampton Baymen's Association.