Was originally considered for the part of Alicia Larde in A Beautiful Mind (2001) because the character in real life is from El Salvador. But the character for the film was later changed to American and given to Jennifer Connelly.
Her brother, Sami, designs custom chairs. His celebrity clients include Jennifer Aniston and her ex-husband, Brad Pitt.
Is the second Latin American actress to be nominated for the Best Actress in a Leading Role Academy Award, for her performance in Frida (2002). Brazilian veteran Fernanda Montenegro was the first, for Central Station (1998).
Was named one of the ten most stylish women in the world by Mr. Blackwell (aka Richard Selzer) in 1997. InStyle named her the most stylish celebrity of 2003 and Eonline.com ranked her as the best dressed female celebrity.
In 2009, musician Prince included a song on his CD "Lotus Flow3r/MPLSound" that is about Salma Hayek. The song shares the same name as her daughter, Valentina.