Became the most popular house-mate among the contestants in the first season of Pinoy Big Brother (2005). Right after his exit from the house, movie and television offers later flowed countlessly and he was later hailed as the newest "heartthrob" of Philippine Cinema.
A member of ABS-CBN's elite circle of homegrown talents, Star Magic co-managed by Cornerstone Entertainment Inc.
Born and raised in Troy, Ohio, Milby is the youngest son of Filipina Elsie Lacia who hails from Surigao Philippines and American entrepreneur, Lloyd Milby.
Was defeated by fellow house-mate Jayson Gainza in their one-on-one eviction in the first edition of Pinoy Big Brother (2005). House-mates nominated him for eviction since he "become too hard headed." However, it had been claimed that fans refused to vote for him to stay inside the house so he could exit sooner than he would want to be (he received 47 percent of the vote). When Sam exited the house, he was stunned by the number of fans that have followed his life inside the Big Brother house.
In 2006, he was launched as a member of all-male group Coverboys with John Lloyd Cruz, Zanjoe Marudo, Rafael Rosell, Victor Basa and Jake Cuenca.