Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Brothers & Sisters

Justin Walker

Kitty McCallister

Sarah Walker

Saul Holden

Holly Harper

Nora Walker

Kevin Walker

Tommy Walker

Paige Whedon

Scotty Wandell

Cooper Whedon

Robert McCallister

Rebecca Harper

Julia Walker

Robert McCallister was the name of a character on a previous Greg Berlanti show, Jack & Bobby (2004) about a boy that grew up to be the President of the United States. As with Brothers & Sisters, he had a wife named Courtney and a son called Jack.

Unusually for a show that turned out to be a critical and commercial hit, in the weeks before the first episode aired, this show went through several cast and crew changes. The Walker family matriarch, Iva, played by Betty Buckley in the original pilot, was recast with Sally Field and renamed Nora. Walker brother Bryan, played by Jonathan LaPaglia, was recast with Matthew Rhys, renamed Kevin, and given a new back story (instead of Bryan being an ex-husband and father who was newly out of the closet, Kevin was a never-married lawyer who was more comfortable with his homosexuality). Marti Noxon was replaced as the showrunner by Greg Berlanti because of "creative differences."

Jeff Bridges was asked to play the part of Sally Field's husband, but turned it down. Jeff's brother Beau was later cast as Sarah's biological father for the last five episodes of the series.