ASadly yes. In Season 4, episode 7, entitled Changing Nature, after a series of very poor decisions by the We Say So corporation, the earth is sent into an ice age that, according to the TV announcer, will last for 10's of thousands of years. As it is commonly known that an ice age killed off the dinosaurs in real life, this reference clearly indicates that everyone died soon after. However, while this episode provides the final chapter of the characters lives, it was not the last new episode to be aired. An additional seven previously unaired episodes were shown in syndication that take place at various undetermined time periods before the ice age begins. As such when viewing series from start to finish, Changing Nature is best watched last.