This movie was inspired by an early 1990s McDonald's ad about Pee-Wee Football that ran during the Super Bowl. The day after it aired, Steven Spielberg liked it so much that he called up the ad's creator, James Ferguson, and hired him to write the script for what became "Little Giants."
During the car wash scene, Hanon is holding up a sign which reads: "Car Wash $5.00..." However, later in the car wash scene, Danny says that the car wash only costs $1.00.
During the final goal-line stand, a close-up is shown on Rudy Zolteck. Junior is standing next to him. When if shifts to Danny only seconds later, Junior is on the bench.