Jennifer Aniston was never in Seattle during shooting of the film. Her face is never seen during the scenes depicting Seattle landmarks, a body double (who always faced away from the camera) was used instead.
When Burke & Eloise are on their first date, they are seen exiting the Water St. Cafe, which is a real restaurant in Vancouver, British Columbia, where parts of the movie were filmed. www.waterstreetcafe.ca
When Eloise takes Burke to visit her mom before the concert, snow can be seen on the roof of a neighbor's house. It isn't seen snowing during any of the scenes prior to that, but several days of rain are shown. Any snow would likely have melted or been dissolved away by then.
When Burke arrives to the hotel for the first time and drinks a vodka on ice, the ice cubes disappear while drinking. Nevertheless, you can still hear the ice cubes.
Eloise chides her assistant for not cauterizing the roses. Roses are never cauterized. That would seal the stems so they would not be able to take up water. Roses in fact should be cut daily since the stems seal up naturally.
Eloise: Can I say something? And, and this comes from a place of total humility. With the acknowledgment that my life is a day-by-day experiment in... really bad decisions. But, er... you're really messed up.