The children of star Julianne Moore and writer/director Bart Freundlich make their movie debuts in "Trust the Man". Caleb Freundlich plays Cosmos, Pamela's son who punches David Duchovny and Liv Freundlich plays Moore's daughter Maggie in the final scenes.
In the scene transitioning to the Christmas holidays, a shot of Central Park is shown with Christo and Jeanne-Claude's The Gates, Central Park, New York City, 1979-2005 in the park. However, this display was unfurled on February 12, 2005 - after the holidays were over.